Sildenafil in heart transplant candidates with pulmonary hypertension

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Intravenous sildenafil in right ventricular dysfunction with pulmonary hypertension following a heart transplant

The objective of the present work is to describe the experience with intravenous (IV) sildenafil in heart transplant (HT) patients with reactive pulmonary hypertension (PH) who developed right ventricular dysfunction (RVD) in the immediate postoperative period. The first 5 patients who received IV sildenafil followinga HT are presented. The HTs took place between March 2011 and September 2012 i...

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Reversible pulmonary hypertension in heart transplant candidates--pretransplant evaluation and outcome after orthotopic heart transplantation.

BACKGROUND Heart transplantation is the most effective treatment for well-selected patients with endstage heart failure. Unfortunately, transplant candidates with pulmonary hypertension (PHT) are often not considered for heart transplantation. This study was performed to assess the value of prostaglandin E(1) (PG-E(1)) for reduction of PHT and to predict the postoperative outcome, compared to p...

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COMPLICATIONS se of Sildenafil in Heart Transplant Recipients With Pulmonary ypertension May Prevent Right Heart Failure

Purpose. We performed a short-term outcome analysis of orthotopic heart transplantation (OHT) in patients with pulmonary hypertension (PH) treated perioperatively with oral sildenafil. Methods. PH (pulmonary vascular resistance 2.5 Wood units, and/or transpulmonary gradient 12 mmHg) was diagnosed in 6 of 25 (group A) heart transplant recipients operated in 2006. This group of patients underwent...

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idiopathic pulmonary arterial hypertension sildenafil

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ژورنال

عنوان ژورنال: Archives of Cardiovascular Diseases

سال: 2015

ISSN: 1875-2136

DOI: 10.1016/j.acvd.2015.01.013